Clinical characteristics analysis of two cases of pediatric vocal cord granulosa cell tumor

Objective:To analyze the clinical characteristics of granulosa cell tumor (GCT) in the vocal cords in children. Methods:The clinical data of 2 children with vocal cord GCT admitted to the Second Affiliated Hospital of Xi'an Jiaotong University from January 2013 to December 2023 were retrospectively analyzed. Results:Case 1, a 6-year-old female, was admitted with a chief complaint of vocal weakness for over 3 months. Under laryngoscopy, diffuse swelling was observed beneath the glottis. Enhanced CT of the neck indicated low-density nodules below the anterior commissure and progressive enhancement. The patient underwent CO2 laser resection under general anesthesia with a supportive laryngoscope, and the postoperative pathological diagnosis was GCT. The patient underwent follow-up examinations at 1 month and 2 years after surgery, and no recurrence of tumor was found, only local scars formed in the laryngeal cavity without obvious adhesions and with good glottal closure. Case 2, an 11-year-old female, was admitted with a chief complaint of hoarseness for over 6 months. Under laryngoscopy, a smooth mass was observed in the anterior commissure. Enhanced CT and MRI of the neck showed a nodular with enhancement in the anterior commissure. The patient underwent CO2 laser resection under general anesthesia with a supportive laryngoscope. The postoperative pathological diagnosis was GCT. Follow-up examinations at 2 weeks and 1 year after surgery showed no recurrence of tumor but scar formation under the glottis with good glottal closure. Conclusion:GCT of the vocal cords in children often presents with disordered voice production, which requires to be confirmed by pathological diagnosis. Surgical resection is the main treatment method, and close follow-up should be paid attention to after surgery.