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    Liu Hongjing, Xie Zhengyi, Zhou Xuyan, Duan Siliang. Research progress of CAR-T cells targeting GPC3 in the treatment of liver cancer[J]. Journal of Guangxi Medical University, 2023, 40(9): 1588-1596. DOI: 10.16190/j.cnki.45-1211/r.2023.09.024
    Citation: Liu Hongjing, Xie Zhengyi, Zhou Xuyan, Duan Siliang. Research progress of CAR-T cells targeting GPC3 in the treatment of liver cancer[J]. Journal of Guangxi Medical University, 2023, 40(9): 1588-1596. DOI: 10.16190/j.cnki.45-1211/r.2023.09.024
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    Research progress of CAR-T cells targeting GPC3 in the treatment of liver cancer

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    • The chimeric antigen receptor T cell(CAR-T)is a new type of immunotherapy method for treating tumors.Glypican-3(GPC3)is highly expressed in hepatocellular carcinoma(HCC)tissue, and has become an ideal target for treating HCC.CAT-T cells targeting GPC3 have significant positive effects on HCC, which is considered one of the most promising immunotherapy.This article reviews the latest research progress in CAR-T cells targeting GPC3 therapy for HCC.
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