Abstract: Chikungunya fever (CHIKF) is an infectious disease caused by Chikungunya virus (CHIKV) infection. The CHIKV is mainly transmitted through the bites of Aedes mosquitoes. The acute symptoms caused by the CHIKV are mainly characterized by fever, rash and severe joint pain. Two vaccines (IXCHIQ and VIMKUNYA) have now been approved for the prevention of CHIKF in key populations, but they have not yet been widely used. At present, there are no specific antiviral drugs approved for marketing against the CHIKV, and clinical treatment mainly focuses on symptomatic supportive therapy. Based on a review of the epidemiology, transmission risks, and prevention and control strategies of the CHIKV, this article focuses on describing the latest progress in the use of Chikungunya vaccines and treatment management.