Abstract: Cardiovascular diseases are the leading cause of death worldwide, and the treatment of cardiovascular diseases has always been of great significance in the medical field. The National Center for Cardiovascular Diseases at Fuwai Hospital, affiliated with the Chinese Academy of Medical Sciences has integrated multidisciplinary expertise and advantages to create a system of percutaneous and non-fluoroscopic procedures (PAN procedures) for treating various structural heart diseases. This approach allows for heart disease treatment"without surgery, radiation, or general anesthesia, "showcasing advantages in patient safety, physician protection, cost-effectiveness, and ease of dissemination. With the advancement of this innovative technology, PAN procedures will gradually be extended to primary-level hospitals, marking a new era in the treatment of structural heart disease.