Abstract: Objective: To observe the clinical effect of rope therapy combined with proprioceptive neuromuscular facilitation(PNF) technique on walking ability of stroke patients. Methods: A total of 60 stroke patients hospitalized in the Rehabilitation Medicine Department of the Second Affiliated Hospital of Guangxi Medical University from January 2022 to July 2022 were selected and divided into conventional group(n=20), PNF group(n=20)and combined group(n=20) according to the random number table method. All patients in the three groups received conventional rehabilitation therapy, the conventional group only received conventional walking rehabilitation training, the PNF group received PNF hand skill training on the basis of conventional training, and the combined group received rope therapy on the basis of conventional and PNF technique training. The BBS score, FMA-LE score, Holden walking functional grading, 10 m walking test(10MWT) and 6 min walking distance(6MWT) assessment results were compared before and after treatment. Results: After 4 weeks of treatment, the BBS score, FMA-LE score, Holden walking function grading, 10MWT and 6MWT assessment indexes in the three groups were better than those before treatment(all P<0.05). Among them, after treatment, the BBS score, FMA-LE score, Holden walking function grading, 10MWT and 6MWT in the PNF group and the combined group were better than those in the conventional group(all P<0.05) and the efficacy of the combined group was better than that of the PNF group(all P<0.05). Conclusion: The walking function of stroke patients with hemiplegia can be further improved by the intervention of rope therapy on the basis of conventional rehabilitation training and PNF technique training.