Abstract: Objective: To analyze the detection rate of non-suicidal self-injury (NSSI) among healthy adoles-cents in China from 2012 to 2022 and the influencing factors of NSSI.Methods: CNKI, WanFang Data, VIP, PubMed, Embase and Medline databases were searched, and the cross-sectional study on influencing factors of adolescent NSSI was included.The retrieval date was from January 2012 to September 2022.Two researchers in-dependently screened the literature and extracted data according to inclusion and exclusion criteria, evaluated the quality of the included literatures, and used Stata SE 17 software to conduct meta-analysis of the data.Results: A total of 14 articles were included, with a total sample size of 67, 006, including 35, 103 boys, 31, 903 girls and 20, 495 non-suicidal self-injuries.Meta-analysis showed that the total detection rate of NSSI among healthy ado-lescents in China was 25%.The detection rate for girls was 26%, while for boys, it was 24%, and the detection rate for girls was 1.07 times that for boys.Among the factors related to society, high social ex-clusion, poor peer relationship and recent life pressure increased the risk of NSSI among adolescents, while high social support reduced the occurrence of this behavior.Among the school-related factors, boarding reduced the risk of NSSI amomg adolescents, while great academic pressure, campus bullying and internet addiction all in-creased the risk of this behavior.Among the family-related factors, the high educational level of the primary care-givers reduced the risk of NSSI amomg adolescents, while the only-child group, single parent, joint family and unreasonable parenting styles all increased the risk of this behavior.Among personal related factors, the severity of depressive symptoms affected the risk of NSSI amomg adolescents.Egger’s test result was P=0.151, and there was no publication bias.Conclusion: The detection rate of NSSI among healthy adolescents in China is high, and adolescent females are the high-risk population of this behavior.Social factors, school factors, family factors and personal factors all affect the occurrence of NSSI among adolescents.