Abstract: Objective:To analyze the incidence and aggregation of cardiovascular disease (CVD) risk factors among different obesity types in middle-aged and elderly residents of Zhuang nationality in Guangxi, so as to provide evidence for the prevention and intervention of CVD in this population.Methods:A cluster sampling method was used to select 1, 650 urban and rural Zhuang residents over 45 years old in Nanning of Guangxi as the study subjects.Body mass index and waist circumference were used as measurement indicators of different obesity types.The subjects were divided into normal group, whole-body obesity group, abdominal obesity group and mixed obesity group.The detection rates of CVD risk factors among different groups were compared.Binary logistic regression and multinomial logistic regression were used to analyze the occurrence and aggregation of CVD risk factors associated with different obesity types, respectively.Results:The results of logistic regression analysis, after adjusting for confounding factors, showed that mixed obesity was a risk factor for hypertension, type 2 diabetes, and blood lipid abnormalities.Compared with the normal weight group, mixed obesity had a statistically significant risk of developing one CVD risk factor(P< 0.05), while abdominal obesity and mixed obesity had a 2.781 times(OR=2.781, 95%CI:1.108-6.984)and 3.416 times(OR=3.416, 95%CI:2.818-4.141)higher risk, respectively, of developing two or more CVD risk factors(P< 0.05).Conclusion:The aggregation of obesity types in middle-aged and elderly residents of Zhuang nationality in Nanning of Guangxi is associated with CVD risk factors, with mixed obesity having the highest impact, followed by abdominal obesity.