退行性脊髓型颈椎病患者术前颈椎矢状面参数与临床结局的相关性

Correlation between preoperative cervical sagittal parameters and clinical outcomes in patients with degenerative cervical myelopathy

  • 摘要: 目的:分析退行性脊髓型颈椎病(DCM)患者术前颈椎矢状面参数与预后的相关性。方法:选取2017 年1 月至2020 年5 月于恩施州中心医院脊柱外科行椎板成形术治疗的102 例DCM 患者。记录患者术前、术后1 年的C2~C7 前凸(CL)、C2~C7矢状垂直轴(CSVA)、T1 斜率(TS)、TS 与CL 差值(TS-CL)、改良的Odom 标准、改良日本骨科协会(mJOA)评分和视觉模拟评分(VAS)。用mJOA 评分改善情况评估DCM 的恢复情况。结果:Pearson 相关分析显示,术后矢状面矫正角度(CL 变化,△CL)与术前CSVA、TS 和TS-CL 均呈负相关关系(r=-0.266、r=-0.286、r=-0.258,P<0.05)。多因素logistic回归分析显示,术前CL 前凸、CSVA≥22 mm、TS-CL≥14.5°为DCM 患者预后不佳的危险因素(P<0.05)。术前CSVA、术前TS-CL 预测DCM 患者预后不佳的受试者工作特征(ROC)曲线下面积(AUC)分别为0.720(95%CI:0.620~0.819)、0.699(95%CI:0.586~0.812)。CSVA<22.45 mm 或TS-CL<21.5°DCM 患者的△CL、改良的Odom 分类、VAS 评分改善、mJOA 评分改善情况均更佳(P<0.005)。结论:椎板成形术前CSVA和TS-CL均为预测DCM患者术后CL变化及预后的有效的颈椎矢状面参数。

     

    Abstract: Objective: To analyze the correlation between preoperative cervical sagittal parameters and prognosis in patients with degenerative cervical myelopathy (DCM).Methods: A total of 102 patients with DCM who underwent laminoplasty in the Department of Spinal Surgery at Enshi Central Hospital from January 2017 to May 2020 were selected.C2-C7 lordosis (CL), C2-C7 sagittal vertical axis (CSVA), T1 slope (TS), difference between TS and CL (TS-Cl), modified Odom's criteria, modified Japanese Orthopaedic Association (mJOA) score, and visual analog scale (VAS) score were recorded before and one year after surgery.The recovery of DCM was evaluated by mJOA recovery rate.Results: Pearson correlation analysis showed that postoperative sagittal plane correction angle (CL change, △CL) was negatively correlated with preoperative CSVA, TS and TS-Cl (r=-0.266, r=-0.286, r=-0.258, P< 0.05).Multivariate logistics analysis showed that preoperative CL lordosis, CSVA ≥ 22mm and TS-CL ≥ 14.5 were risk factors for poor prognosis in DCM patients (P< 0.05).The area under receiver operating characteristic (ROC) curve (AUC) of preoperative CSVA and preoperative TS-CL for predicting poor prognosis in DCM patients were 0.720 (95% CI:0.620-0.819) and 0.699 (95% CI:0.586-0.812), respectively.The △CL, modified Odom's classification, VAS score improvement and mJOA score improvement were better in patients with CSVA< 22.45mm or TS-CL< 21.5° DCM (P< 0.005).Conclusion: Both CSVA and TS-CL before laminoplasty are effective cervical sagittal plane parameters for predicting postoperative CL changes and prognosis in DCM patients.

     

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