Abstract: Objective: To analyze the correlation between disease status of oral lichen planus (OLP) patients and the levels of anxiety, depression and personality traits, and to provide reference for the prevention and treatment of this disease.Methods: From February 2017 to March 2018, 34 patients with erosive oral lichen planus (EOLP), 46 patients with non-erosive oral lichen planus (NE-OLP) and 52 healthy volunteers were evaluated to analyze the relationship between disease status of OLP and the levels of anxiety, depression and certain personality traits by Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and Eysenck Personality Questionnaire (EPQ).Results: The positive rates of anxiety (47.06%) and depression (52.94%) in the E-OLP group were higher than those in the healthy control group (both P< 0.05).Logistic regression analysis showed that whether OLP patients were positive for anxiety and depression or not was correlated with semi-quantitative reticulate-erosive-ulcerative (REU) scores (OR=1.809, 95% CI:1.072-3.054; OR=1.663, 95% CI:1.068-2.589) and N-dimension scores (OR=1.233, 95% CI:1.086-1.400; OR=1.211, 95% CI:1.068-1.374) (all P< 0.05).Multiple linear regression analysis showed that SAS scores and SDS scores were correlated with disease duration and N-dimension scores (all P< 0.05).OLP patients had a lower composition ratio of polycythemia than those in the healthy control group (P=0.009).Conclusion: The personality traits of OLP patients are correlated with the level of anxiety/depression symptoms.OLP patients are emotionally unstable and tend to have introverted personality traits.With the increase of REU scores and Eysenck neuroticism scores, OLP patients are more prone to anxiety and depression, especially erosive OLP patients.