Abstract: Objective: To understand the socio-demographic characteristics, clinicopathological characteristics and medical service utilization of lung cancer in Guangxi, and to provide scientific basis for the screening and diagnosis of lung cancer.Methods: A retrospective study was conducted to analyze the data of socio-demographic characteristics, clinical characteristics, medical service utilization, medical expenses and other data of primary lung cancer patients admitted to a cancer hospital in Guangxi from 2005 to 2014, and to analyze the trend in ten years with trend χ² test.Results: A total of 1000 patients with lung cancer were included.The average age of diagnosis was 69.73±11.05 years old, the ratio of male to female was 2.38:1, and the sex ratio of lung cancer gradually decreased.The proportion of patients aged 45-59 years increased from 13.00%in 2005 to 35.00%in 2014, and the proportion of patients aged ≥60 years decreased from 86.00% to 61.00% (P＜0.05).The number of lung cancer patients participating in medical insurance for urban residents and employees as well as New Rural Co-operative Medical System increased, while the proportion of self-funded patients decreased year by year (P＜0.05).From 2005 to 2014, the use of chest CT, head MR, head CT and bone scan showed an increasing trend, while the use of chest X-ray and neck ultrasound showed a decreasing trend(all P＜0.05).The per cap-ita and per time average diagnosis and treatment cost as well as average daily hospitalization cost showed an increasing trend, the drug cost accounted for the largest proportion of hospitalization cost, and its changing trend was consistent with that of per capita diagnosis and treatment cost.Conclusion: From 2005 to 2014, the male and female proportion of lung cancer in Guangxi decreases, and the age of onset tends to be younger.The main methods of detection and diagnosis of lung cancer have changed, and the increase of drug and laboratory fees has led to the continuous rise of diagnosis and treatment costs, but the main treatment regimens have not changed.