Abstract: Graded management of antineoplastic drugs is the core link to regulate the management of clinical use of antineoplastic drugs and improve the level of rational drug use. “The Administrative Measures for the Clinical Application of Antineoplastic Drugs (Trial)” issued by the National Health Commission of the People's Republic of China requires each region to formulate a graded management catalog of antineoplastic drugs in the region.In addition, “the Management Indicators for the Rational Clinical Use of Antineoplastic Drugs (2021 Edition)” also requires a unified graded management catalog for each region.Based on this, the Evidence-based Pharmacy Professional Committee of Guangxi Pharmaceutical Association organized multidisciplinary experts to discuss the hot topics such as the graded management catalog of antineoplastic drugs and prescription authority, and finally formed an expert consensus in combination with the reality of Guangxi, so as to provide guidance for the graded management of antineoplastic drugs in medical institutions in Guangxi.